USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: EEA1_HUMAN USC-OGP 2-DE database:  EEA1_HUMAN EEA1_HUMAN General information about the entry View entry in simple text format Entry name EEA1_HUMAN Primary accession number Q15075 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Early endosome antigen 1; AltName: Full=Endosome-associated protein p162; AltName: Full=Zinc finger FYVE domain-containing protein 2;. Gene name Name=EEA1 Synonyms=ZFYVE2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1092: pI=5.57; Mw=174213 Cross-references UniProtKB/Swiss-Prot Q15075; EEA1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name EEA1_HUMAN Primary accession number Q15075 Secondary accession number(s) Q14221 Sequence was last modified on  May 5, 2009 (version 2) Annotations were last modified on  February 15, 2017 (version 151) Name and origin of the protein Description RecName: Full=Early endosome antigen 1; AltName: Full=Endosome-associated protein p162; AltName: Full=Zinc finger FYVE domain-containing protein 2; Gene name Name=EEA1 Synonyms=ZFYVE2 Encoded on Name=EEA1; Synonyms=ZFYVE2 Keywords 3D-structure; Coiled coil; Complete proteome; Cytoplasm; Direct protein sequencing; Endosome; Membrane; Metal-binding; Phosphoprotein; Polymorphism; Reference proteome; Zinc; Zinc-finger. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL L40157; AAA79121.1; -; mRNA EMBL X78998; CAA55632.1; -; mRNA EMBL AC016136; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC021646; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC026111; -; NOT_ANNOTATED_CDS; Genomic_DNA CCDS CCDS31874.1; -; . PIR A57013; A57013; . RefSeq NP_003557.2; NM_003566.3; . UniGene Hs.567367; -; . PDB 1HYI; NMR; -; A=1347-1411 PDB 1HYJ; NMR; -; A=1347-1411 PDB 1JOC; X-ray; 2.20 A; A/B=1287-1324 A/B=1326-1411 PDB; 3MJH; X-ray; 2.03 A B/D=36-69 PDBsum; 1HYI; -; . PDBsum 1HYJ; -; . PDBsum 1JOC; -; . PDBsum 3MJH; -; . ProteinModelPortal Q15075; -; . SMR Q15075; -; . BioGrid 113999; 38; . IntAct Q15075; 50; . MINT MINT-5004646; -; . STRING 9606.ENSP00000317955; -; . iPTMnet Q15075; -; . PhosphoSitePlus Q15075; -; . SwissPalm Q15075; -; . BioMuta EEA1; -; . DMDM 229462866; -; . EPD Q15075; -; . MaxQB Q15075; -; . PaxDb Q15075; -; . PeptideAtlas Q15075; -; . PRIDE Q15075; -; . DNASU 8411; -; . Ensembl ENST00000322349; ENSP00000317955; ENSG00000102189; . GeneID 8411; -; . KEGG hsa:8411; -; . UCSC uc001tck.4; human; . CTD 8411; -; . DisGeNET 8411; -; . GeneCards EEA1; -; . HGNC HGNC:3185; EEA1; . HPA CAB005861; -; . HPA CAB018782; -; . HPA HPA038158; -; . HPA HPA038159; -; . MIM 605070; gene; . neXtProt NX_Q15075; -; . OpenTargets ENSG00000102189; -; . PharmGKB PA27621; -; . eggNOG ENOG410IFA7; Eukaryota; . eggNOG ENOG4111F3Q; LUCA; . GeneTree ENSGT00730000110715; -; . HOGENOM HOG000112329; -; . HOVERGEN HBG039440; -; . InParanoid Q15075; -; . KO K12478; -; . OMA NANSEAT; -; . OrthoDB EOG091G01M6; -; . PhylomeDB Q15075; -; . TreeFam TF329698; -; . Reactome R-HSA-168138; Toll Like Receptor 9 (TLR9) Cascade; . SIGNOR Q15075; -; . ChiTaRS EEA1; human; . EvolutionaryTrace Q15075; -; . GeneWiki EEA1; -; . GenomeRNAi 8411; -; . PMAP-CutDB Q15075; -; . PRO PR:Q15075; -; . Proteomes UP000005640; Chromosome 12; . Bgee ENSG00000102189; -; . CleanEx HS_EEA1; -; . ExpressionAtlas Q15075; baseline and differential; . Genevisible Q15075; HS; . GO GO:0044308; C:axonal spine; IEA:Ensembl; . GO GO:0005737; C:cytoplasm; TAS:ProtInc; . GO GO:0005829; C:cytosol; IDA:UniProtKB; . GO GO:0005769; C:early endosome; IDA:UniProtKB; . GO GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0019897; C:extrinsic component of plasma membrane; IDA:UniProtKB; . GO GO:0016020; C:membrane; TAS:ProtInc; . GO GO:0098793; C:presynapse; IEA:GOC; . GO GO:0055037; C:recycling endosome; IEA:Ensembl; . GO GO:0005969; C:serine-pyruvate aminotransferase complex; IEA:Ensembl; . GO GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB; . GO GO:0005516; F:calmodulin binding; NAS:UniProtKB; . GO GO:0030742; F:GTP-dependent protein binding; IDA:UniProtKB; . GO GO:0042803; F:protein homodimerization activity; IDA:UniProtKB; . GO GO:0008270; F:zinc ion binding; TAS:UniProtKB; . GO GO:0045022; P:early endosome to late endosome transport; NAS:UniProtKB; . GO GO:0006897; P:endocytosis; IMP:UniProtKB; . GO GO:0016189; P:synaptic vesicle to endosome fusion; TAS:UniProtKB; . GO GO:0006906; P:vesicle fusion; IMP:UniProtKB; . GO GO:0039694; P:viral RNA genome replication; IMP:ParkinsonsUK-UCL; . Gene3D 3.30.40.10; -; 1; . InterPro IPR007087; Znf_C2H2; . InterPro IPR000306; Znf_FYVE; . InterPro IPR017455; Znf_FYVE-rel; . InterPro IPR011011; Znf_FYVE_PHD; . InterPro IPR013083; Znf_RING/FYVE/PHD; . Pfam PF01363; FYVE; 1; . SMART SM00064; FYVE; 1; . SUPFAM SSF57903; SSF57903; 1; . PROSITE PS50178; ZF_FYVE; 1; . PROSITE PS00028; ZINC_FINGER_C2H2_1; 1; . PROSITE PS50157; ZINC_FINGER_C2H2_2; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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